To emphasize the difference, the following points underline the key difference between Islam and this secular system, in particular, and other social and political systems, in general are highlighted.The first point is, Islam differs from secularism’s theories and perspectives in its ideological and doctrinal bases. Islam is a Divine Message with a special conception of the universe, life and man. It basically disagrees with secular views, which have their roots in their materialistic vision that has no religious base, nor any belief in Allah. Capitalism is merely concepts on devoid of spiritual and moral values. The difference between it and Islam is obviously great. Islam has an all-embracing ideological and legislative make-up. In it, no barriers are to be found between morals, laws, worships, concepts and existence.There are significant differences among them in terms of emphasis they place on material or spiritual goals and the role of moral values and government intention in ordering human affairs. While material goals concentrate primarily on goods and services that contribute to physical comfort and well-being, spiritual goals include nearness to God, peace of mind, inner happiness, honesty, justice, mutual care and cooperation, family and social harmony, and the absence of crime and anomie. These may not be quantifiable, but are, nevertheless, crucial for realizing human well-being may lead to a neglect of spiritual ingredients. The greater the difference in emphasis, the greater may be the difference in the economic disciplines of these societies.